Tag Archives: develop

Mass. General researchers develop 3-D ‘mini-gut’ model to study response to gluten

In pursuit of a novel tool for the research and treatment of celiac disease, scientists at the Mucosal Immunology and Biology Research Center (MIBRC) at Massachusetts General Hospital (MGH) have validated the use of intestinal organoids. These 3-D tissue cultures are miniature, simplified versions of the intestine produced in vitro. Taking tissue from duodenal biopsies of celiac… Read More »

Gene-editing tool CRISPR repurposed to develop better antibiotics

A University of Wisconsin-Madison researcher and his collaborators at the University of California, San Francisco have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ones. Resistance to current antibiotics by disease-causing pathogens is a growing problem, one estimated… Read More »